To examine the effect of halobetasol propionateon (HBP) on hypothalamic-pituitary-adrenal (HPA) axis in patients, a study of 12-to-16-year-olds with stable plaque psoriasis covering $10% of their body surface area were enrolled. HBP lotion was applied twice a day for up to 2 weeks. Cosyntropin stimulation test was used to determine cortisol levels at the time of screening and at the end of the study to evaluate HPA axis response.
Learn more at the Journal of the American Academy of Dermatology International.